As we have more connected devices in more places, it seems that there are 2 types of vacation strategies emerging.
Put on your out of office message, don't sign up for meetings, etc., but be available by phone if necessary (assuming people respect that), and do "email triage" so you are staying on top of things, but you're not spending your vacation tied to your phone.
The Check Out
Don't check email, don't take calls...nothing. Of course, as I was saying to someone yesterday, "if you check out, be prepared to dig out."
I tend to do the "Integrated," you?